The area around what is now the Town of Marble City was considered part of Lovely County, Arkansas Territory until 1829.

In that year, the Federal Government began moving the Western Cherokees from other parts of Arkansas Territory into this area, then called Nicksville.

Non-Indian settlers were ordered to vacate, and the Arkansas Territorial Legislature ended its claim to the land.

The Ozark Marble Company operated the quarry from 1906 to 1914, producing material for building construction.

Another was the Administration Hall at Rice Institute, which is now Lovett Hall at Rice University: it is made of red St. Joe bricks made in Louisiana with clay from Buffalo Bayou in Houston, Texas; pink granite from Llano, Texas; and gray marble from Marble City, Oklahoma.

[5] According to the United States Census Bureau, the town has a total area of 0.4 square miles (1.0 km2), all land.

The Citizens State Bank and Dwight Presbyterian Mission are located in Town of Marble City.