Dwight Mission is a census-designated place (CDP) in Sequoyah County, Oklahoma, United States.

[4] The original Dwight Mission was established in August 1820 on Illinois Bayou, near present-day Russellville, Arkansas, in the Cherokee settlements.

Timothy Dwight, President of Yale University and an influential member of the American Board of Commissioners for Foreign Missions.

[4] In 1828 the Western Cherokees were forced to move out of Arkansas into Indian Territory (present day Oklahoma).

As a result of this move, Dwight Mission was reestablished on Sallisaw Creek, in Sequoyah County in the Marble City, Oklahoma area.

The mission consisted of twenty-one houses, a large dining hall, a barn, and outbuildings.