The Caruthersville Bridge is a single tower cantilever bridge carrying Interstate 155 and U.S. Route 412 across the Mississippi River between Caruthersville, Missouri, and Dyersburg, Tennessee.

[2] A committee was created by both state legislatures to study the possibility of constructing the bridge in 1949.

[3] The site was chosen by the commission on November 18, 1952,[4] which was subsequently approved by the Army Corps of Engineers on August 20, 1953.

It is also the only bridge to connect the states of Missouri and Tennessee directly.

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