Casualty series 28

[2] This series saw the departures of Tom Kent (Oliver Coleman), Sam Nicholls (Charlotte Salt), Jamie Collier (Daniel Anthony) and Adrian "Fletch" Fletcher (Alex Walkinshaw), and temporary departures of Zoe Hanna (Sunetra Sarker) and Kathleen "Dixie Dixon (Jane Hazlegrove).

This series also welcomed Lily Chao (Crystal Yu), Rita Freeman (Chloe Howman), Ethan Hardy (George Rainsford), Caleb Knight (Richard Winsor) and Ben "Lofty" Chiltern (Lee Mead); as well as the returns of Holby City character, Connie Beauchamp (Amanda Mealing), and paramedics Iain Dean (Michael Stevenson) and Tamzin Bayle (Gemma Atkinson).

Oliver Coleman stars as Tom Kent, an emergency pediatrician, and Charles Dale features as Big Mac, a hospital porter.

Jane Hazlegrove plays Kathleen "Dixie" Dixon, a paramedic and the operational duty manager at Holby Ambulance Service.

Amanda Henderson portrays staff nurse Robyn Miller and Tony Marshall and Azuka Oforka appear as Noel Garcia and Louise Tyler, the department's receptionists.

Charlotte Salt plays Sam Nicholls, a CT2 doctor, and Sunetra Sarker portrays Zoe Hanna, a consultant and the department's clinical lead.

On 30 July 2013, it was announced that actresses Crystal Yu and Chloe Howman had joined the show's regular cast for this series.

[4] Kent remarked that her casting was a notable one for the show and called Blackman's role "a fantastically witty and charming character".

[4] Michael Stevenson reprised his role as Iain Dean; he previously appeared in series 26 as the former Army colleague of Sam who she had an affair with.

[8] The castings of George Rainsford and Richard Winsor, in the respective roles of Ethan Hardy and Caleb Knight, were announced in September 2013.

[10] Davood Ghadami guest stars in two early episodes of the series as gay Iranian asylum seeker Ramin Tehrani.

Mealing had played Connie in the show's spin-off series Holby City for six years until 2010, and had also made appearances in Casualty during crossover events.

[15] John Michie regularly guest stars as his Holby City character Guy Self from episode 31, as part of Connie's introduction and ongoing story.

Robyn's new year gets off to a strange start as she treats a singer claiming to have lost his voice and Charlie spends a frustrating evening desperately trying to contact his son, Louie.

Honor Blackman guest stars in the opening episode.
Michelle Collins starts a guest role in episode 44.