The Eastern Siouan branch consists of various historical languages spoken by Siouan peoples of the Appalachian Plateau and Piedmont regions of present-day Virginia and the Carolinas.

Eastern Siouan languages were historically spoken by the Catawba and Waccamaw people.

They possibly represent a dialect continuum with Ohio Valley Siouan languages (Ofo language/Mosopelea, Biloxi language).

Recognized members of the Eastern Siouan/Catawban family include:

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