Catfish Creek is a 3.83 mi (6.16 km) long 2nd order tributary to Chartiers Creek in Washington County, Pennsylvania.

Catfish Creek rises about 0.5 miles west of Laboratory, Pennsylvania, and then flows northwest through the City of Washington to join Chartiers Creek in Washington.

[3] Catfish Run drains 4.69 square miles (12.1 km2) of area, receives about 39.0 in/year of precipitation, has a wetness index of 357.21, and is about 20% forested.

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