Cave Creek is a stream in Cooper County in the U.S. state of Missouri.
The stream headwaters arise at 38°49′23″N 92°35′27″W / 38.82306°N 92.59083°W / 38.82306; -92.59083[1] at an elevation of 870 feet and approximately one-half mile north of Prairie Home.
[2] The stream flows to the north-northwest for about four miles and then turns to the northeast.
It continues to the northeast for about three miles to its confluence with the Petite Saline Creek near Gooch Mill.
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