Communities served include: Cave Spring High School opened in 1956.

Cave Spring held grades 10-12 for numerous years until 2002, when it fed approximately half of its 10-12 population into Hidden Valley High School after it was completed and first opened.

In 2019, the high school underwent a $43.3 million renovation, with the "new" Cave Spring opening its doors in August 2020.

Cave Spring athletes are known as the "Cave Spring Knights" and compete in the Virginia High School League's River Ridge District in regular season play, primarily against other schools in the Roanoke and New River Valleys.

The Knights have won team state titles in: Notable athletic alumni include: