[5] Pulaski County High School offers 9 Advanced Placement courses: English Language and Composition, English Literature and Composition, Art History, Studio Art, Calculus, Environmental Science, U.S. Government and Politics, U.S. History, and Psychology.

The school also features an on-site Career and Technical Education Center, which offers a number of vocational courses in the fields of: agriculture, business, marketing, early childhood education, fashion, nutrition and wellness, culinary arts, nursing, construction and building trades, computer aided design, auto repair, cosmetology, electricity, video production, and welding.

As a member of the Roanoke Valley District and the Northwest Region, Pulaski County defeated Thomas Dale High School to capture the Group AAA, Division 6 football state championship in 1992[9] under the direction of former West Virginia University assistant Joel Hicks.

[10] In 1993, Pulaski County was ranked as one of the top 25 high school football teams in the country by USA Today for most of the season.

In 2008, Pulaski County High School had a perfect 10–0 regular season, winning the River Ridge District in the process.

Pulaski County has also produced such well-known athletes and coaches such as: former Washington Redskins receiver Gary Clark,[11] New Orleans Saints kicker Shayne Graham, former Dallas Cowboys and Georgia Bulldogs football and current Louisville Cardinals defensive coordinator Todd Grantham, and[12] Carolina Panthers and Virginia Tech star player Jeff King.

In 2004, the Cougar Basketball team under the direction of Coach Mark Hanks journeyed to the Group AA playoffs for the first time since the early 1990s.

Hanks took two years off while serving solely as the athletic director, he returned to the court in 2011 to coach the men's team.

Particularly on January 1, 2008, at 7:30 p.m. the Lady Cougars defeated the River Ridge District number one ranked team the Hidden Valley Titans.

Led by coach Brenda King, the Lady Cougars snapped the Hidden Valley High School (Virginia) Titans' 38 game winning streak.

The school also does a Senior vs Faculty basketball game every year, in which the proceeds go to the charity of the winning team's choice.

Similarly, the original musical, The Other Side of the Story, about the villains of renowned fictional stories and their misjudged reputations, also won a State Championship; its script was written by Mr. McCoy, with assistance from students, with the music and arrangements written collaboratively by Josh O'Dell and Mr. McCoy.

The PCHS Drama Department has also performed at the American High School Theater Festival in Edinburgh, Scotland.

The program has received many awards ranging from marching band and concert ensembles to the indoor winter performing groups.

Emphasis on hard work and musicianship is what makes the Golden Cougar Band "The Pride of Pulaski County."

In 1978, the boys' cross country team under Coach David Wright won the Roanoke Valley District title with a 10–0 record.