She was educated at the University of Lviv (now in Ukraine), where she obtained a doctorate of medicine.

[2] She studied the menstrual cycle, cellular respiration, and embryology,[3] and served as chief scientific officer of the Agricultural Research Council of Great Britain.

[4] Lutwak-Mann was known for discovering that the hormone progesterone acts on the placenta to control carbonic anhydrase synthesis.

[5] She also co-authored the then-reference text on male reproductive function and semen ("Male Reproductive Function and Semen: Themes and Trends in Physiology, Biochemistry and Investigative Andrology", 1981) with Thaddeus Mann.

[6] Lutwak-Mann married Thaddeus Mann in 1934, after they met in medical school.