Cell Painting

The Cell Painting assay[1] is a high-content, high-throughput imaging technique used to capture a wide array of cellular phenotypes in response to diverse perturbations.

[2] These phenotypes, often termed "morphological profiles", can be used to understand various biological phenomena, including cellular responses to genetic changes, drug treatments, and other environmental changes.

[8] Given its ability to capture a wide array of cellular responses, the Cell Painting assay has become a powerful tool in the field of drug discovery.

[15] With advancements in imaging technology and machine learning, the resolution and depth of morphological profiles are expected to increase, allowing for even more detailed insights into cellular biology.

Additionally, as the scientific community continues to generate data using the Cell Painting assay, there's a push towards creating shared repositories to facilitate collaborative research and data-driven discoveries.