[3][4] Located in Clinton County, it serves DeWitt, Grand Mound, Low Moor, and Welton.

[6] The District was formed in 1958 with the schools in DeWitt, Grand Mound, Welton, and Low Moor.

Ekstrand Elementary School is located in DeWitt and serves students in pre-kindergarten through grade 3.

[citation needed] When a new school was planned and built in the autumn of 1959, the three-story building was reconfigured into a junior high.

By the late 1980s it was decided that the junior high school building was becoming too costly to maintain and was too expensive to bring up to code.

Construction of the new facilities began in November 2007, and includes a new cafeteria, remodeled kitchen space, and new alternative classroom.

[10] Central DeWitt formerly competed in the WaMaC Conference, a league of Class 3A and several larger Class 2A schools spanning from east-central to northeast Iowa, where they had a great rivalry with the Maquoketa Cardinals, especially in football; the arrangement began in 2003, when the old Big Bend Conference dissolved and several of that league's former schools migrated to the WaMaC.

In the latter half of the 2010s, upon news that Burlington was leaving the Mississippi Athletic Conference, Central DeWitt officials began a process to join the MAC, citing travel distance and competition factors.

In 1995, the district closed the original building because it was deemed to be structurally unsafe and its roof was in a poor condition.

[23] The district at one time considered expanding Welton Elementary to upper elementary levels but decided against it since it deemed the building too out of date and architecturally difficult to renovate, citing narrow staircases which would have difficulty accommodating chairlifts and the multi-story design.

A historic newspaper was found inside the cornerstone, and the City of Welton government received the school memorabilia.