The Chamber of Commerce in Douala, Cameroon is a building constructed between 1927 and 1928 under the French mandate, under the umbrella of the League of Nations.

It is among the earliest architectural testimonies of the early French era, within the framework of the Mandate, under the umbrella of the League of Nations, after Germany was defeated in September 1918.

Its mission was to give account of the resources dedicated to development, and also to fix the market prices lists for the farmers.

The fifteen members of the Chamber were chosen by the Commissioner of the Republic, and appointed for two years through an arrêté.

At the entrance of the edifice, there is a plate that commemorates General Charles de Gaulle's visit to Cameroon in 1940.