[4] The Charlestown Village Historic District, Middle Pickering Rural Historic District, Martin-Little House, Oskar G. Stonorov House, John Williams Farm, and Jacob Wisner House are listed on the National Register of Historic Places.

As of the census[8] of 2000, there were 4,051 people, 1,340 households, and 1,003 families living in the township.

20.4% of all households were made up of individuals, and 5.8% had someone living alone who was 65 years of age or older.

[9] The Pennsylvania Turnpike, also known as I-76, is the main highway serving Charlestown Township.

Pennsylvania Route 401 follows Conestoga Road on a northwest-southeast alignment through the southwestern portion of the township.

The township is served by Great Valley School District.