It was serialized in Media Factory's Comic Cune from June 2016, to December 2020, and is licensed in English by Yen Press.

Written and illustrated by Tamamushi Oku, Cheerful Amnesia was serialized in Media Factory's Comic Cune magazine from June 27, 2016, to December 26, 2020.

[6] For Anime News Network's Fall 2023 Manga Guide, Rebecca Silverman gave the first volume a 3 out of 5, noting that "the four-panel format works well here, although the humor does rely on a lot of repetition that can get a little old.

", while Christopher Farris gave it a 3.5 out of 5, summarizing "there should be a place for lesbian love stories to have their own shamelessly stupid, kinda-horny comedies, and Cheerful Amnesia fills that role enjoyably enough.

As a volume, I felt so desperately sad for Mari who has the body of her lover back, with the soul of a gaping child inhabiting it."