[5][6] CHKD is a 206-bed hospital and serves the medical and surgical needs of children throughout the greater Hampton Roads metro area, the Eastern Shore of Virginia and northeastern North Carolina.

It is also part of CHKD Health System, offering a network of comprehensive pediatric services in more than 40 locations that stretch from Williamsburg, VA, to Elizabeth City, NC.

In 1896, a group of Christian women formed the Norfolk City Union of The King's Daughters to provide medical care for indigent mothers and their children.

Today, the CHKD Health System operates primary care pediatric practices, surgical practices, urgent care centers,[8] multi-service Health Centers and satellite offices throughout its service region.

In July 2018, a multidisciplinary Health Department team conducted a follow-up site visit to verify the hospital's adherence to Virginia trauma center standards.