Choline-phosphate cytidylyltransferase (EC 2.7.7.15) is an enzyme that catalyzes the chemical reaction where the two substrates of this enzyme are CTP and choline phosphate, and the two products are diphosphate and CDP-choline.
It is responsible for regulating phosphatidylcholine content in membranes.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases).
The systematic name of this enzyme class is CTP:choline-phosphate cytidylyltransferase.
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1PEH and 1PEI.