Choline bitartrate is an organic compound with the chemical formula [(CH3)3NCH2CH2OH]+HOOC−CH(OH)−CH(OH)−COO−.

Choline bitartrate is used as a dietary supplement, a food additive, a nutrient and as a lipotropic compound.

[1] Certain conducted double-blind, placebo-controlled studies of the effects of choline bitartrate treatment against Alzheimer-type dementias suggest improvement in some areas of patients' cognitive performance.

If swallowed in high doses, may cause dizziness, nausea, vomiting and diarrhea, and a rotten fish-like body smell resulting from the excretion of trimethylamine from the body (trimethylamine is a choline metabolite).

There are reports of depression or increased symptoms of it in patients using high doses of choline bitartrate.