The first masses were said in a rented hall on the northeast corner of Cedar and Purchase Streets in Rye beginning on June 6, 1880.

[1] Designed by architects Henry D. Murphy and Edward Lehmann, the massive Gothic Revival structure was dubbed the "Cathedral of Westchester".

Once the church moved to its present site, the school building was converted into a residence for nuns, before becoming a private apartment house, which it remains today.

The current grammar school building, designed in the Tudor Revival style, was built behind the church, with frontage along Milton Road.

In 1950, the Academy of the Resurrection, an all-girls preparatory school, was opened, adjacent to the church property along Boston Post Road.