The group is also present in Rome, Turin, Brescia, Bergamo, Cagliari, Parma, Busto Arsizio, Gallarate, Voghera, Palermo, Monza, Campomarino, Novara, Como, Varese, Genoa, Albenga, Savona, Lecco and Lecce; since 2014, they have also been active in Lugano, Mendrisio and Chiasso, Switzerland.

In 2008, the Ambrogino was awarded to the honorary City Angel Edward "Eddie" Gardner, a Ghanaian man who risked dying on July 20 of that year after being stabbed, in a racist attack, by three drug dealers shouting "dirty nigger!"

They are the only non-profit association in Italy also involved in preventing and fighting street crime, in cooperation with law enforcement agents.

The City Angels of Italy and Switzerland are founding members of Eunwa (European neighbourhood watch association), based in Vienna, Austria.

After passing an aptitude test, the candidate has to compile the application for admission, pay an annual insurance fee and handle the following documents: certificate of good health, passport photos, photocopy of identity card.

The self-defense used by City Angels is called Wilding, has been created by the founder Mario Furlan and is based on psychology and instinct.

From their birth, City Angels have been organizing public initiatives to promote tolerance, solidarity, anti-racism and brotherhood among people.

Among their events, the multi-religious prayer the day before Christmas and Easter in the Milan Central Station in front of the Shoah Memorial: representatives of various religions (priests, imams, rabbis, Protestant pastors, ...) pray together in the middle of the homeless.