Clarksdale High School (CHS) is the public high school of Clarksdale, Mississippi and a part of the Clarksdale Municipal School District.

[3] Around the time of racial integration, circa the 1960s, there had been plans to build a new consolidated Clarksdale-Coahoma County High School to serve all children in Coahoma County; plans were abandoned, even though the building was already constructed, because the officials wanted to maintain segregation in a de facto manner.

[4] After Clarksdale High integrated racially (sometime around 1970) the school administration refused to allow students to do a black history week, a frequent practice at schools for black people.

As a result, 80 students walked out of classes in protest.

[5] In the early 20th century the school band, organized by Simon Kooyman, won Mississippi state championships and was named a Goodwill Ambassador to the city.