Cleome oxalidea is a species of plant in the Cleomaceae family and is found in Western Australia.

[1] The annual or ephemeral herb has a rosetted habit and typically grows to a height of 5 to 30 centimetres (2.0 to 11.8 in).

It blooms between January and September producing blue-pink-purple flowers.

It is found in the Kimberley, Pilbara, Goldfields-Esperance and Mid West regions of Western Australia growing in stony sandy-loam alluvium.

The C4 pathway in this species evolved independently from the two other C4 Cleome species, C. angustifolia and C.