1O91129512837ENSG00000144810ENSMUSG00000068196P27658Q00780NM_001850NM_020351NM_007739NP_001841NP_065084NP_031765Collagen alpha-1(VIII) chain is a protein that in humans is encoded by the COL8A1 gene.

[5][6] This gene encodes one of the two alpha chains of type VIII collagen.

The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium.

The type VIII collagen fibril can be either a homo- or a heterotrimer.

Alternatively spliced transcript variants encoding the same isoform have been observed.