Colle Sannita (Campanian: Ro Còllë) is a comune (municipality) in the Province of Benevento in the Italian region Campania, located about 80 kilometres (50 mi) northeast of Naples and about 25 kilometres (16 mi) north of Benevento.

Colle Sannita borders the following municipalities: Baselice, Castelpagano, Castelvetere in Val Fortore, Circello, Reino, Riccia, San Marco dei Cavoti.

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