The road runs parallel to the Atlantic Ocean in Miami Beach, Florida, one block west.

Collins Avenue is home to many historic Art Deco hotels, and several nightclubs to the north.

[2] The annual Miami International Boat Show occurs on Collins Avenue.

On February 2, 1973, a mentally ill man firebombed a cafeteria at 1921 Collins Avenue in Miami Beach, killing three people and injuring over 130.

On June 24, 2021, an apartment building at 8777 Collins Avenue in Surfside partially collapsed, resulting in 98 fatalities.