Colombia competed in the 2019 Pan American Games in Lima, Peru from July 26 to August 11, 2019.

[3] During the opening ceremony of the games, boxer Yuberjen Martínez carried the flag of the country as part of the parade of nations.

[22] Colombia qualified a women's team (of 18 athletes) by finishing in one of the three qualification spots at the 2018 Copa América Femenina.

Colombia qualified a full team of 6 athletes through the 2018 Pan American Squash Championships.

Colombia qualified three surfers (two men and one women) in the sport's debut at the Pan American Games.