[2] The community and post office were named for Thomas Cuthbertson, a family friend of the Bozemans.

[1] By the early 1920s, Cuthbert had a church, two stores, a blacksmith shop, a cotton gin, telephone office, and a school.

A post office, two businesses, and a population of twenty-five were reported at the community in 1936, the year that its school was consolidated with that of Colorado City.

After World War II, the improvement of rural roads in the area led to Cuthbert's decline as it lost its trade to Colorado City.

The Cuthbert post office was discontinued circa 1960, when the town reported one business and a population of twenty-five.