Cuyler is a town in Cortland County, New York, United States.

The East Branch of the Tioughnioga River flows southwest through the town.

New York State Route 13 is a northeast-southwest highway in Cuyler.

There were 406 housing units at an average density of 9.3 per square mile (3.6/km2).

There are zero Asians or African Americans living in Cuyler as of the 2020 census.