Preble is a town in Cortland County, New York, United States.

[4] The town is named after Commodore Edward Preble, a naval hero.

The First Presbyterian Church and Little York Pavilion are listed on the National Register of Historic Places.

The West Branch of the Tioughnioga River flows southward through the town past the previously mentioned highways.

The northern town line is the border of Onondaga County (Tully).

22.0% of all households were made up of individuals, and 7.8% had someone living alone who was 65 years of age or older.