It was concluded that LAP can deliver at least one of the triggering signals necessary for inducing macrophage activity that leads to cytostasis.
Cystostatic concentrations of n-3 and n-6 PUFA did not induce apoptosis, but did cause permanent cellular growth arrest by effecting the cell cycle.
Study shows that metabolites of the lipoxygenase pathway are involved with the antiproliferation induce by PUFA.
[7] Cytostatic agents have been beneficial in fighting tumors with their ability to induce cell growth arrest.
After administration, they are expelled from the body through urine and feces, which ultimately reach wastewater systems, posing a risk to the aquatic ecosystem.