DNA-3-methyladenine glycosylase II (EC 3.2.2.21) is an enzyme[1][2][3][4] that catalyses the following chemical reaction: Involved in the removal of alkylated bases from DNA in Escherichia coli.
Through the process of convergent evolution, there are at least two unrelated protein folds that share the same DNA-3-methyladenine glycosylase activity.
The first, the AlkA N-terminal domain, is found in bacteria Pfam PF06029.
The second, methylpurine-DNA glycosylase (MPG) Pfam PF02245 is found in vertebrates including humans.
This enzyme-related article is a stub.