On 1 May 2000, Nicholls began presenting the live broadcast ITV Day of Promise show with Eamonn Holmes and Carol Vorderman.
[citation needed] In 2004, Nicholls presented on Tyne Tees the series, The Unprofessionals, where, along with co-presenter Giles Vickers-Smith, she was given different challenges, including pole dancing,[10] a children's party entertainer, a drain unblocker and a taxidermist.
[citation needed] Nicholls became one of the presenters of Text2Date,[6] a programme that encouraged participants to meet and date using mobile phone text messages.
Nicholls' guest appearances on programmes include Trisha, The Last Word, This Morning, Bedrock, Boys & Girls, Dick & Dom in da Bungalow, Sport on 5 and Granada Soccer Night.
She was also the voice behind the late night documentary series about North West nightlife called Party Fever which was shown on Granada.
[citation needed] As well as the annual pantomime performances, in 2004 she also starred on stage in the Hammond Production Group's The Young Ones Summer Holiday in Worthing.