Member of the National Academy of Sciences (2019) Transatlantic Medal, Society for Endocrinology (2021) Adolf Windaus Prize, Falk Foundation (2022) Endocrinology Massachusetts General Hospital Harvard Medical School Baylor College of Medicine Korea Advanced Institute of Science and Technology David Dudley Moore (born August 21, 1952) is an American molecular biologist known for his work investigating nuclear hormone receptors.

[7] Moore began work as a postdoctoral researcher in 1979 in the laboratory of Howard Goodman in the Department of Biochemistry and Biophysics at the University of California, San Francisco, where he studied the genetic sequence of human growth hormone and the DNA binding activity of the glucocorticoid receptor.

[16] In 1997, Moore was recruited to the Department of Molecular and Cellular Biology, then headed by Bert W. O'Malley, at Baylor College of Medicine in Houston, Texas.

There, he identified the bile acid and xenobiotic ligands of farnesoid X-receptor, an orphan nuclear receptor he had first purified in 1995, and an upstream regulator of SHP.

[13][18] The discovery of bile acid ligands for FXR led Moore and colleagues to demonstrate a strong link between nuclear hormone receptors and liver disease.