Tapping into her Mexican heritage,[2] "De Una Vez" marks Gomez's first Spanish single, with production from Tainy, Albert Hype, and Jota Rosa.

It is a rhythmic pop and alternative R&B song with urban elements, discussing themes of love, self-worth, emotional growth, and empowerment.

Heavily inspired by her Latin American culture, the mystical video adapts the art style of magic realism and depicts Gomez with a glowing milagro resembling the Sacred Heart, chronicling her personal evolution and healing.

"De Una Vez" reached top-ten in Costa Rica, Panama, Paraguay, Venezuela, US Hot Latin Songs, and the top-forty on the Billboard Global 200.

[4] Various murals were spotted in Mexico, stating the song titles "De Una Vez" and "Baila Conmigo", generating speculating amidst fans and mainstream media that Gomez would be releasing Latin music soon.

[16] As "De Una Vez" steers Gomez into a new phase in her music career, she wanted the song's visuals to have an impact on viewers, handled by directors that can deeply connect to the material.

Wanting to create an emotional journey with the video, Verduzco explained that they "thought that the song had a sincere and personal message, more of the woman than the artist.

To channel this idea, Gomez and Los Pérez looked at popular Latin American writers Isabel Allende, Gabriel García Márquez, and Laura Esquivel, whose literary works delved into supernatural concepts of magical realism, an art genre that blends real-world problems with elements of fantasy.

Styled by Shirley Kurata, Gomez wears a soft-pink floral Rodarte dress, with a V-neck, puffed sleeves, and pink, white and yellow daisy prints.

Her wavy hair is adorned with Frida Kahlo-inspired flower accessories made from silk, paired with feathered opal earrings from Mexican designer Daniela Villegas.