"Lose You to Love Me" is a pop ballad with empowering lyrics about discovering one's true self, backed by a choir, piano and strings.

Outside of the United States, "Lose You to Love Me" topped the charts in Canada and the Republic of Ireland, and peaked within the top ten of the charts in many countries, including Australia, Belgium, Germany, Malaysia, the Netherlands, New Zealand, Norway, Singapore, Sweden, Switzerland, and the United Kingdom.

It is a simplistic black-and-white video directed by Sophie Muller and filmed entirely on an iPhone 11 Pro in Los Angeles.

[4] In an interview with Zane Lowe on his Beats1 Radio show, co-writer Julia Michaels revealed that the song was written on Valentine's Day of 2019.

Chris Monlanpy from Slate stated "with only piano and Gomez's voice, then grows ever more stirring with plucked strings, a choir of backing vocals, and, more than halfway through, a subtle heartbeat thump that's the closest thing to a beat in the whole song.

"[6] The song debuted at number 15 on the US Billboard Hot 100 with 36,000 copies sold in its opening week after just two days of tracking.

The black-and-white music video was directed by Sophie Muller and filmed entirely on an iPhone 11 Pro in Los Angeles.

[15][16] Writing for Vogue, Michelle Ruiz commended the song, stating, "Potentially getting lost in the internet sleuthing of it all, however, is the fact that "Lose You to Love Me" is a highly catchy and searing ballad that deserves to immediately be added to everyone's Empowering Breakup Songs playlist, right after Lizzo's 'Truth Hurts'.