He was named as a SuperPrep All-Midwest honoree and an All-State selection by both the Chicago Tribune and Champaign-News Gazette.

[4] Lowry ultimately elected to take the scholarship offer of Northwestern and played in all 13 games that year as a backup to future Minnesota Vikings defensive end Tyler Scott.

During a game against Vanderbilt, he had one fumble recovery, one quarterback hurry, two solo tackles, and a pass deflection on the line of scrimmage.

He missed the game against Nebraska to injury; however, he did have his first career touchdown on an interception return against Maine.

He was named to the Academic All-Big Ten team and an honorable mention by league coaches.

[12] Lowry was selected by the Green Bay Packers in the fourth round (137 overall) of the 2016 NFL draft with the second of two compensatory picks.

[13] Rob Demovsky, a staff writer for ESPN, commented that he was surprised that general manager Ted Thompson ignored the offense this far in the draft.

Eliot Wolf, president of the Green Bay Packers football operations, said in the regards to his pick that he believed Lowry was "an underrated athlete".

[15] On December 3, 2017, in a 26–20 victory over the Tampa Bay Buccaneers, Lowry recovered a Jameis Winston fumble and returned it for the first touchdown in his career in the NFL.

[18] In week 15 of the 2019 season against the Chicago Bears, Lowry recorded his first career interception off a pass thrown by Mitch Trubisky during the 21–13 win.