He played college football at Arkansas and was selected by the Patriots in the fourth round of the 2017 NFL draft.

[1] His three-star recruitment prospect rating earned Wise offers from Arkansas, Texas A&M, Vanderbilt, Arizona, Purdue and Wake Forest.

[5][6] Wise recorded eight combined tackles, 1.5 sacks, four quarterback pressures, and a forced fumble during their 10–3 victory over the East.

The Patriots then went on to defeat the Jacksonville Jaguars in the American Football Conference Championship Game to advance to Super Bowl LII where they would go on to lose 41–33 to the Philadelphia Eagles.

Wise helped the Patriots reach Super Bowl LIII where they beat the Los Angeles Rams 13–3.

[13] In Week 3 of the 2020 season against the Las Vegas Raiders, Wise strip sacked Derek Carr and recovered the football in the end zone for his first career touchdown during the 36–20 win.