[3] Ekuale entered his redshirt senior season on the watch list for the Polynesian College Football Player of the Year and made 17 tackles (3.5 for loss) and one sack while starting 12 of WSU's 13 games.

[9] Ekuale was removed from the practice squad on December 6, 2018, after receiving a four-game suspension for violating the NFL's performance-enhancing substance policy.

[12] The Browns placed Ekuale on injured reserve after sustaining a calf injury while playing against the New England Patriots in Week 8.

[16] In Week 13 against the Minnesota Vikings, Ekuale recorded his first career sack on Kirk Cousins during the 27–24 overtime loss.

[19] Ekuale spent the entire 2021 regular season on the Patriots' practice squad, but was elevated to the 53-man roster a total of eight times.