He played college football at Virginia Tech and signed as an undrafted free agent with the New York Giants in 2019.

Slye has also been a member of the Carolina Panthers, Houston Texans, San Francisco 49ers, Washington Commanders, and Jacksonville Jaguars.

[2] Slye played four seasons for the Virginia Tech Hokies, opting to join the team as a walk-on over a scholarship offer from James Madison.

[3] After going unselected in the 2018 NFL draft, Slye participated in a tryout for the Tampa Bay Buccaneers and received interest from the Cleveland Browns, but was not signed by either team.

[8] Although originally brought in to serve as a "camp leg", Slye made seven of eight field goal attempts in the preseason, including three from beyond 50 yards out.

[16] In Week 7 against the New Orleans Saints, Slye attempted an NFL record 65-yard field goal with 1:55 remaining in the 4th quarter, but was short by a few inches as the Panthers lost 27–24.

[18] In Week 12 against the Minnesota Vikings, Slye missed another game winning field goal with four seconds remaining from 54 yards as the Panthers lost 28–27.

[27] In Week 12 against the Seattle Seahawks, Slye suffered a hamstring injury after a blocked extra point attempt and was placed on injured reserve the following day.

[31] In Week 10 of the 2022 NFL season against the 8–0 Philadelphia Eagles, Slye played a key part in Washington's 32–21 upset win.

[34][35] In Week 8 of the 2023 season, Slye set a Commanders franchise record for the longest field goal made at 61 yards.