Demini River is a river in the Amazon rainforest of the state of Amazonas, Brazil.

The Demini River rises in the Serra do Aracá State Park, a 1,818,700 hectares (4,494,000 acres) conservation unit created in 1990.

[1] The Toototobi River is a tributary of the upper part of the Demini near the headwaters of the Orinoco near the border of Venezuela.

The Yanomami índios are native to this area.

This article related to a river in the Brazilian state of Amazonas is a stub.