Injection of dermal fillers is the second most common nonsurgical cosmetic procedure in the USA, used for addressing volume deficiency, scars, wrinkles, and enhancing facial features and specific anatomical sites like the lips.
The variety of available dermal fillers increases annually, requiring dermatologists and cosmetic surgeons to stay informed about the latest options to ensure safe and effective treatments.
[1] Fillers are made of polysaccharides such as hyaluronic acids, a naturally occurring in skin and cartilage,[2] collagens which may come from pigs, cows, cadavers, or may be generated in a laboratory,[3] the person's own transplanted fat tissue, and/or biosynthetic polymers.
The studies explore various methods and parameters for characterizing dermal fillers, providing key insights for clinicians to select the most suitable products for their patients.
The aging face undergoes complex changes due to bone resorption, gravity, fat redistribution, and skin damage, which dermal fillers aim to counteract.
HA fillers are considered medical devices rather than medicines, thus lacking stringent regulatory requirements for safety and efficacy data.
[14] More rarely, serious adverse effects such as blindness due to retrograde (opposite the direction of normal blood flow) embolization into the ophthalmic and retinal arteries can occur.
What defines a qualified dermal injection provider varies by country and is a point of debate between board-certified doctors and injectors who operate under cosmetic or aesthetician licenses.
[19] In China, the market of cosmetic surgery increase in recent 10 years, NMPA (formerly CFDA) also has issued several guidance to regulate injectable filler.