It is an isomer of thiosulfurous acid but is lower in energy.

[1] Unlike many of these other reduced sulfur acids, dihydroxydisulfane can be formed in a pure state by reacting hydrogen sulfide with sulfur dioxide at −70 °C in dichlorodifluoromethane.

[2] Dihyroxydisulfane may exist in an equilibrium with thiosulfurous acid.

The conjugate bases are called disulfanediolate HS2O−2 and hypodithionite S2O2−2.

[7] Related compounds include the isoelectronic substances hydrogen tetroxide HOOOOH, hydroxotrisulfane HOSSSH, HSOSSH, and tetrasulfane HSSSSH.