He played the young and beautiful, fashion-loving heroine Zhou Yiyi's boyfriend Cha Jian.
[3] In 2018, Ding gained attention for his supporting role of Dongfang Bubai in the drama New Smiling Proud Wanderer.
[12] Ding started gaining increased popularity for starring in these two dramas, receiving the title of "May Boyfriend".
In November 2024, Ding Yuxi reunited with co-star Yu Shuxin in Love Game in Eastern Fantasy based on the novel The Guide to Capturing a Black Lotus premiering on Tencent Video and WeTV.
[16] Due to his huge skyrocket in popularity from this role, he was invited to cover "Ning Mou (凝眸)" (originally performed by Zhang Yuan), a song from the Love Game in Eastern Fantasy OST, on the music competition show he was hosting, The Next Singer.