Diphepanol is a cough suppressant (antitussive).

Ex 1: The α-keto bromination of propiophenone [93-55-0] (1) gives 2-bromopropiophenone [2114-00-3] (2).

Displacement of the halogen and hence amination with piperidine [110-89-4] gave alpha-Piperidinopropiophenone, CID:458526 (3).

and addition of phenyl Grignard reagent to give the benzhydrol product, and hence Dihepanol (4).

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