It now has similar demographics to its western neighbor Potrero Hill – an upper middle-class working professional neighborhood.

Dogpatch is located on the eastern side of the city, adjacent to the waterfront of the San Francisco Bay, and to the east of Potrero Hill.

Its Caltrain station at 22nd Street makes Dogpatch popular with commuters who work south of San Francisco.

The Third Street corridor connects Dogpatch to San Francisco's downtown, via new development zones including Mission Bay and the UCSF research campus.

Notable sites in the neighborhood include Irving M. Scott School, the oldest public school building in San Francisco, built 1895; the historic shipyards at Pier 70; a boxing gym, where many local amateurs train; a number of restaurants & breweries; Esprit Park, a sunny lawn with bordering trees that was donated to the city by Esprit Corp.;[6] the headquarters of the San Francisco chapter of Hells Angels; and numerous historical residences.

Because it survived the 1906 earthquake and fire relatively undamaged, and until recently had not been redeveloped, Dogpatch has some of the oldest houses in San Francisco, dating from the 1860s.

[citation needed] Dogpatch was uninhabited land for much of its history, used sporadically by Native Americans as hunting ground.

Townsend, a good friend of de Haro, approached him about dividing his land into individual lots and selling them.

De Haro, with his land rights already challenged and fearing that the United States government would now strip him of Potrero Nuevo, agreed to Townsend's suggestion.

Together with famed surveyor Jasper O'Farrell, recent emigrant Cornelius De Boom, and Captain John Sutter hashed out the grid and street names.

Historians speculate that "merging the United States with the counties of California would attract homesick easterners" and their newly acquired gold-rush riches to settle in the neighborhood.

[13] By the standard of the mid-nineteenth century, Potrero Hill was not a convenient location to get to - it was still separated by Mission Bay, which was not yet filled in.

Prospective buyers partly deemed Potrero Hill too far away and were wary of de Haro's uncertainty as legal owner of the land.

Residents of Potrero Point celebrated with bonfires after learning of the outcome, some of whom gained title to the lot where they squatted through the Squatter's Rights.

[14] Potrero Point experienced a minor boom in housing as factory workers preferred to live nearby.

In 1862, President Abraham Lincoln signed into law the Pacific Railway Act that provided Federal government support for the building of the First transcontinental railroad.

The Long Bridge was closed after Mission Bay was filled in the early 1900s, which made Dogpatch an even more desirable location.

The United States' decision to enter World War II created an industrial boom in Dogpatch, led by the shipyards that constructed navy ships.

To obtain the necessary land for the freeways, some residents were forced to vacate their homes in exchange for significantly below-market price paid by the government.

Interstate 280 sliced through Potrero Nuevo, and the area east of the freeway began to form a unique identity.

The construction of Oracle Park in the late 1990s contributed to the gentrification, and many high-rise, high rent apartment buildings were built near the ballpark.

The Museum of Craft and Design (MCD) opened in the historic American Industrial Center on 3rd Street bringing local, national, and international artist representation to the neighborhood.