Outer Mission is a small residential neighborhood on the south edge of San Francisco, bounded by Geneva Avenue (on the northeast), Interstate 280 (on the northwest), Mission Street (on the southwest), and the city of Daly City (on the south).

The Cayuga Improvement Association (CIA) covers the area bounded by Interstate 280, Mission Street, Sickles and Onondaga.

Its surrounding neighborhoods in San Francisco include Ingleside to the west, Mission Terrace to the north, Excelsior to the northeast, and Crocker-Amazon to the southeast.

Outer Mission is southwest of Geneva Avenue, and due west of the Cow Palace.

Before the area was developed it largely consisted of farms, providing the city with Swiss chard and potatoes.

The 1990s to 2000s housing bubble and its subsequent gentrification led to many Latino/Chicano and Asian/Filipino families to move into the area: It remains one of the few low-rent and middle class enclaves in San Francisco.

During peak hours, the 88 BART Shuttle Muni line passes through the Outer Mission and can be used to get to Balboa Park quickly and directly.