It was built in 1992 by the South Carolina Department of Transportation and was designed by HNTB Corporation.

The bridge provides a connection between the communities east of the Cooper River, including Mount Pleasant and Daniel Island, to North Charleston and I-26.

The Don Holt Bridge is adjacent to a Kapstone (formerly MeadWestvaco) paper mill.

The lawsuit was settled by mandating that a road weather information system (RWIS) be included in the bridge project.

[2] The bridge was named for Don N. Holt who served in the South Carolina House of Representatives and was in the insurance business.