Doxercalciferol (or 1-hydroxyergocalciferol, trade name Hectorol) is drug for secondary hyperparathyroidism and metabolic bone disease.

[1] It is a synthetic analog of ergocalciferol (vitamin D2).

It suppresses parathyroid synthesis and secretion.

[2] Doxercalciferol is the vitamin D2 analogue of alfacalcidol.

[3] It undergoes 25-hydroxylation in the liver to become the active ercalcitriol, without the involvement of kidneys.