Drnholec (German: Dürnholz) is a market town in Břeclav District in the South Moravian Region of the Czech Republic.

The market town is situated on the banks of the Thaya River.

The western tip of the Nové Mlýny reservoirs, built on the Thaya, extends into the territory of Drnholec.

They had rebuilt the local dilapidated castle into a Renaissance aristocratic residence and expanded the estate.

[8] The Drnholec Castle has a Gothic core from the 14th century, which was rebuilt in the Renaissance style in 1583.