The Dugdemona River rises west of Simsboro in western Lincoln Parish, and flows generally southeastwardly through Bienville, Jackson, Winn and Grant parishes, through a portion of the Kisatchie National Forest.

It joins Castor Creek to form the Little River about 3 miles (4.8 km) northeast of Georgetown.

[3] A short tributary known as the Little Dugdemona River[4] flows southwestwardly through Jackson and Bienville parishes.

[3] At Joyce, LA, the river has a mean annual discharge of 835 cubic feet per second.

[5] According to the Geographic Names Information System, the Dugdemona River has also been known historically as:[6]